Science fiction is now a multifaceted, heterogeneous and universal genre, perhaps the most complex “mode of expression and behavior” going beyond the boundaries of a particular genre, while spreading throughout a variety of media (literature, film, television, theater, video games). We invite authors to contribute to this special issue with unique perspectives about one of the most long-lived, thought-provoking, artistically provocative and economically relevant audiovisual genres of all times.